Transplantation: Treatment of Parkinson’s Disease Essay -- Health Medi

Transplantation: Treatment of Parkinson’s Disease Parkinson’s disease (PD) is a slowly-progressive disease which ultimately robs its victims of voluntary motor control. The disease manifests itself as a series of symptoms which include "bradykinesia, rigidity, tremor, and impairment of postural reflexes (Fitzgerald, 1992:215)". It is a result of a loss of neurons in the substantia nigra pars compacta (SNpc). Chemotherapy, in the form of drugs such as levodopa and carbidopa, has been effective in alleviating many of the symptoms in the early stages of PD; however, with increasing losses in the number of cells in SNpc, such therapy becomes more and more ineffective. New therapies, using selegiline (deprenyl) and antioxidants (tocopherol or Vitamin E) focus on halting the progression of the disease by potentially salvaging surviving SNpc cells (Ahlskog, 1990). A more aggressive approach in the treatment of PD has surfaced in recent years. Researchers are experimenting with the prospects of transplanting tissue directly into the afflicted areas of the central nervous system (CNS) of PD patients. In both animal models of PD and humans, marginally successful transplants have been performed using adrenal chromaffin cells and fetal neurons. Genetically-altered, dopamine-producing tissues are currently being proposed as an alternative in transplant therapy of PD. As techniques become more refined, such "brain-grafting" may be the panacea for not only PD, but also for other debilitating diseases such as Huntington’s disease and Alzheimer’s disease. According to Fitzgerald (1992:215), the "cardinal pathological feature [of PD] is loss of neurons from the substantia nigra". Most of this loss occurs in the SNpc, of which approxima... ...zgerald, M. J. T. Neuroanatomy: Basic and Clinical. London: Bailliere Tindall, 1992. Freed, C. R. et.al. 1992. Improved drug responsiveness following fetal tissue implant for Parkinson’s disease. Neurochemistry International, 20: 321S-327S. Freed, C. R. et.al. 1990. Transplantation of human fetal dopamine cells for Parkinson’s disease. Fetal Human Transplant, 47:505-12. Freed, W. J. et.al. 1991. Brain grafts and Parkinson’s disease. Journal of Cellular Biochemistry, 45:261-7. Hurtig, H. et.al. 1989. Postmortem analysis of adrenal-medulla-to caudate autograft in a patient with Parkinson’s disease. Annals of Neurology, 25(6):607-13. Kordower, J. H. et.al. 1991. Putative chromaffin cell survival and enhanced host-derived TH-fiber innervation following a functional adrenal medulla autograft for Parkinson’s disease. Annals of Neurology, 29(4):405-12.

Human Resource Challenges and Practices in IT Industry

Proceedings of the 5th National Conference; INDIACom-2011 Computing For Nation Development, March 10 – 11, 2011 Bharati Vidyapeeth? s Institute of Computer Applications and Management, New Delhi Human Resource Challenges & Practices in IT Industry Rakesh S. Patil1, Varsha Patil2 and Pratibha Waje 3 1 Head and 3Lecturer 1,3 Sir Visvesvaraya Institute of Technology, Chincholi (Sinner) Nashik-422 101 (MS) 2 SNG Institute of Management & Technology, Rajgurunagar, Pune (MS) 1 [email  protected] com and [email  protected] om ABSTRACT The need of organizations for people and people for organizations will be more difficult to satisfy in the today’s competitive business environment. Organization’s competitive advantage could be generated from human resources (HR) and organization performance is influenced by a set of effective HRM practices. Software is a wealth and job creating industry, which has in just a few years, grown to US $ 1 trillion, employing millions of p rofessionals worldwide. The Indian software industry has burgeoned, showing a nearly 50% compounded annual growth rate over the recent years.Being a knowledge-based industry, a high intellectual capital lends competitive advantage to a firm. With a global explosion in market-opportunities in the IT sector, the shortage of manpower both in numbers and skills is a prime challenge for HR professionals. The related issues are varied indeed: recruitment of world-class workforce and their retention, compensation and career planning, technological obsolescence and employee turnover. This paper explains the HR challenges and practices in software Industries. KEYWORDS HRM, IT,HR Strategy, Services 1. INTRODUCTION The economy has transitioned to what some call „The Age of Information? an economy in which gross domestic product is increasingly dominated by services. Services permeate every aspect of our lives. We use transportation services; restaurant services; hotels; electricity and t elephones; postal, courier and maintenance services; services of hairdressers; services of public relations and advertising firms; lawyers; physicians; dentists; stockbrokers and insurance agents; movie theatres; and swimming pools . When we do buy goods, such as new car or a washing machine, we often still rely on services to keep them running and repair them when they break down.Services allow us to budget our time as well as our money. â€Å"The twentieth century was the age of machine; the twenty-first century will be the age of people† Buzzwords like globalization, empowerment, cross functional teams, downsizing, learning organizations and knowledge workers are changing the way of life of managers and the way they manage people. 2. STRATEGIES & POLICIES OF SOFTWARE INDUSTRIES: 1. Motivation & Retention of Employees Retention and motivation of personnel are major HR concerns today.People a Gartner group company specializing in management of human capital in IT organizatio ns has observed that the average tenure for an IT professional is less than three years. Further, the use of new technologies, the support of learning and training, and a challenging environment ranked higher than competitive pay structures as effective retention practices. Our own recent survey of 1028 software professionals from 14 Indian software companies, showed that while the professional gave importance to personal and cultural job-fit, HR managers believed that the key to retention was salary and career satisfaction.Money was a prime motivator for ‘starters', but for those into their third or fourth jobs, their value-addition to the organization was more important. Monetarily, offering ‘the best salaries in industry' is the minimum every company is doing, apart from performancebased bonuses, long-service awards, and stock options. Many organizations frequently conduct employee satisfaction and organization climate surveys, and are setting up Manpower Allocation C ells (MAC) to assign ‘the right project to the right person'.In fact, some are even helping employees with their personal and domestic responsibilities to satisfy & motivate their workforce! 2. Best Talent Attraction In a tight job market, many organizations often experience precipitous and simultaneous demands for the same kinds of professionals. In their quest for manpower, they are cajoling talent around the world. In such a seller's market, software companies are striving to understand which organizational, job, and reward factors contribute to attracting the best talent one having the right blend of technical and person-bound skills.This would mean a knowledge of ‘the tools of the trade' combined with conceptualization and communication skills, capacity for analytical and logical thinking, leadership and team building, creativity and innovation. The Indian software industry suffers from a shortage of experienced people such as systems analysts and project managers, and attracting them is a key HR challenge. 3. Compensation and Reward Increasing demands of technology coupled with a short supply of professionals (with the requisite expertise) has increased the costs of delivering the technology.This makes incentive compensation a significant feature, with the result that software Copy Right  © INDIACom-2011 ISSN 0973-7529 ISBN 978-93-80544-00-7 Proceedings of the 5th National Conference; INDIACom-2011 companies have moved from conventional pay-for-time methods to a combination of pay-for-knowledge and pay-forperformance plans. With the determinants of pay being profit, performance and value-addition, emphasis is now on profit sharing (employee stock option plans) or performance-based pay, keeping in view the long-term organizational objectives rather than short-term production-based bonuses.Skills, competencies, and commitment supercede loyalty, hard work and length of service. This pressurizes HR teams to devise optimized compensation package s, although compensation is not the motivator in this industry. 4. Increasing loyalty and commitment As with any other professional, what really matters to software professionals is selecting ‘the best place to work with', which is what every company is striving to be. The global nature of this industry, and the ‘project-environment' has added new cultural dimensions to these firms.In a value-driven culture, values are determined and shared throughout the organization. Typically, areas in which values are expressed are: performance, competence, competitiveness, innovation, teamwork, quality, customer service, and care and consideration for people. Flat structure, open and informal culture, authority based on expertise and ability rather than position, and flexi-timings are some of the norms software firms follow. The idea is to make the work place a ‘fun place' with the hope of increasing loyalty and commitment. 5.The Demand Supply Gap Shortage of IT professionals is global in nature and not peculiar to the Indian software industry alone. W. Strigel, founder of Software Productivity Centre Inc. (1999) has projected the shortage of software professionals to be one million by 2006. In fact, a survey reports that 75 per cent of US companies planned to reengineer their applications using newer technologies, but found that 72 per cent of their existing staff lacked the skills needed in these technologies, and 14 per cent were not even retrainable. Graph No. 1.Annual demand for IT Professionals For India, it is predicted that in the year 2004 itself, the IT sector will need 1,95,000 professionals. This trend will continue, and in the year 2010 almost 3,70,000 IT professionals will be required (Strategic Review Reports, NASSCOM 19962001). Consequently, recruitment managers are exploring new sources of IT manpower from non-IT professional sectors, as well fresh, trainable science graduates. 6. Integrating HR strategy with Business Strategy The strate gic HR role focuses on aligning HR practices with business strategy.The HR professional is expected to be a strategic partner contributing to the success of business plans, which to a great extent depend on HR policies pertaining to recruitment, retention, motivation, and reward. The other major areas of concern for HR personnel in this context are, management of change, matching resources to future business requirements, organizational effectiveness, and employee development. 7. Encouraging Quality and Customer focus Today? s corporate culture needs to actively support quality and customer orientation.With globalization and rapid technological change, quality is of utmost importance for the Indian companies, which earn most of their revenues through exports. Hence, the HR professional as a strategic partner needs to encourage a culture of superior quality to ensure customer satisfaction, the only real measure of quality of a product or service. To be competitive today, an organizat ion needs to be customer responsive. Responsiveness includes innovation, quick decision-making, leading an industry in price or value, and effectively linking with suppliers and vendors to build a value chain for customers.Employee attitudes correlate highly with customer attitude. The shift to a customer focus redirects attention from the firm to the value chain in which it is embedded. HR practices within a firm should consequently be extended to suppliers and customers outside the firm. 8. Value Addition training for up-gradation of Skills Rapid and unpredictable technological changes, and the increased emphasis on quality of services are compelling software businesses to recruit adaptable and competent employees.Software professionals themselves expect their employers provide them with all the training they may need in order to perform not only in their current projects, but also in related ones that they may subsequently hold within the organization. As observed by Watts Humphr ey, Fellow of the Carnegie Mellon University, â€Å"as software professionals gain competence, they do not necessarily gain motivation. This is because a creative engineer or scientist who has learned how to accomplish something has little interest in doing it again.Once they have satisfied their curiosity, they may abruptly lose interest and seek an immediate change†. And when the rate of technological change is high may be higher than the time required to acquire competence in one area professionals could undergo psychological turbulence owing to the need to work in a new technology throughout their career. They want to gain new knowledge, which will be utilized by their organization. On the basis of the new learning they want to work in higher segments of software value chain. Therefore, constant up-Copy Right  © INDIACom-2011 ISSN 0973-7529 ISBN 978-93-80544-00-7 Human Resource Challenges & Practices in IT Industry gradation of employee skills poses yet another challeng e for HR personnel. 3. CHALLENGES FOR IT INDUSTRY: The main challenges to the IT Industry are i. Recruitment planning ii. Performance management iii. Training and development iv. Compensation management v. HRM as whole 1. Recruitment Planning: Recruitment planning is most important component in new people management with special reference to IT industry.We have to deal with human assets so it becomes important and have good quality of people in the organization. We have to take the recruitment planning in very serious manner to ensure that we can get best talent in the organization. 2. Performance management: Now the challenges how to manage the performance of your employees. You have to get right person in a organization to manage your business. The challenge should be to create a performance culture where you can provide opportunities for enhance performance, where optimum performance becomes a way life. 3.Training and development: This is another challenging area in IT industry. We have to chalk out a suitable strategy for training & development so that employees are well equipped to handle the challenges in advance. 4. Compensation management: The IT industry is one of the high paying industries. This is very competitive industry, we have to attract best talent, offer best possible compensation package to the employees. Now IT companies are having ESOP with the compensation package. But the really challenge should be how we are able to incorporate all the subsystems in HR.Ultimately this would help the organization for achieving exceptional performance. People have to be groomed to get in with the performance culture. We have to create an environment that stimulates the creation of knowledge, its sustenance will be the challenge for IT companies in the future. HR department cannot function with traditional systems. Now the role will shift to HR facilitator, to facilitate change process. HR facilitator will have to involve the whole organization in this pro cess and act as a guide, coach, counselor and facilitator.Any organization in the IT industry will have to face these challenges like Infosys, Satyam, Pentafour, DSQ Software, Micro soft India, Intel India. These IT companies are leaders in their own stride. They have excellent recruitment policies, huge data bank, and placement agencies. They are also having rigorous tests to ensure that they can get high profile talent that will fit in their culture. They have best performance system that evaluates the organization as whole. They have been able to tackle the quantum of performance with fairly efficient manner.The prime tasks for these IT companies are to build corporate culture. They are diverting all the efforts to build performance driven culture. The major issue for these companies to get right man for right job. We have to find person with the required skills, experiences, mindsets, and also he must be suitable for these organizations. 5. Attrition and Retention: IT companies are having high degree of attrition. The challenges for these companies are to keep this attrition rate as low as possible. Various companies adopt different techniques to retain their employees like high pay packets, ESOP, other benefits.So we have to keep this attrition rate as low as possible to retain super achievers. CONCLUSION With the advent of a work situation where more and more companies are having to concede that their valued employees are leaving them, a new concept of career and human resource management is bound to emerge. The focus of this new paradigm should not only be to attract, motivate and retain key ‘knowledge workers', but also on how to reinvent careers when the loyalty of the employees is to their ‘brain ware' rather than to the organization.With lifetime employment in one company not on the agenda of most employees, jobs will become short term. Today's hightech employees desire a continuous up-gradation of skills, and want work to be exciting an d entertaining a trend that requires designing work systems that fulfill such expectations. As employees gain greater expertise and control over their careers, they would reinvest their gain back into their work. HR practitioners must also play a proactive role in software industry. As business partners, they need to be aware of business strategies, and the opportunities and threats facing the organization.As strategists, HR professionals require to achieve integration and fit to an organization's business strategy. As interventionists, they need to adopt an allembracing approach to understanding organizational issues, and their effect on people. Finally, as innovators, they should introduce new processes and procedures, which they believe will increase organizational effectiveness REFERENCES [1]. Noe, R. A. , Hollenbeck, J. R. , Gerhart, B. and Patrick, P. M. (2007) â€Å"Human Resource Management: Gaining aCompetitive Advantage†, Tata McGraw-Hill, New Delhi. 2]. Prasad, K. (2005) â€Å"Strategic Human Resource Management: Text and Cases†, Macmillan India Ltd. , New Delhi. [3]. Kandula,Srinivas R. (2003) â€Å"Human Resource Management in practice with 300 models : Techniques and Tools†, Sage, Delhi [4]. Rao T. V. , Rao Raju, and Yadav Tara. (2001). â€Å"A Study of HRD concepts, structure of HRD Copy Right  © INDIACom-2011 ISSN 0973-7529 ISBN 978-93-80544-00-7 Proceedings of the 5th National Conference; INDIACom-2011 [5]. [6]. [7]. [8]. [9]. [10]. [11]. [12]. [13]. [14]. [15]. epartments, and HRD practices in India†, Vikalpa, ol 261, No. 1, Jan. -Mar Page 49-62. Siekel Tom. (2002). â€Å"After CRM, it’s ERM: Employee Relationship Management Indian Management†, Vol. 41, Issue 9, July p. 38 Storey J. (ed. ) (1989). â€Å"New Perspectives in Human Resource Management†, Routledge, London, p. 114. Truss Catherine. (2001). â€Å"Shifting the paradigm in Human Resource Management: From the resource based view to c omplex adaptive system†. Published in a Research Paper on Human Resource Management by Kingston Business School, Kingston University Thite, M. 2004) â€Å"Managing People in the New Economy: Targeted HR Practices that Persuade People to Unlock their Knowledge Power†, Response Books, New Delhi. Truss, C. (2001) â€Å"Complexities and Controversies in Linking HRM with Organizational Outcomes† Journal of Management Studies, Vol. 38, No. 8. Walker, J. W. and Stopper, W. G. (2000) â€Å"Developing Human Resource Leaders† Human Resource Planning, Vol. 23, No. 1, p. 38-44. Webb, J. (2004) â€Å"Putting Management Back into Performance: A Handbook for Managers and Supervisors†, Allen & Unwin, Australia.Joynt, P. and Morton, B. (2005) â€Å"The Global HR Manager: Creating the Seamless Organization†, Jaico Publishing House, Mumbai. Jyothi, P. and Venkatesh, D. N. (2006) â€Å"Human Resource Management†, Oxford University Press, New Delhi. Kandol a, R. and Fullerton, J. (1994) â€Å"Managing the Mosaic: Diversity in Action†, IPD, London. Kandula, S. R. (2004), â€Å"Human Resource Management in Practice: With 300 Models, Techniques and Tools†, Prentice Hall of India Private Limited, New Delhi. Copy Right  © INDIACom-2011 ISSN 0973-7529 ISBN 978-93-80544-00-7

Chinua Achebe s Things Fall Apart - 972 Words

Jacen Buensalida Mrs. Smith English December 7, 2015 Unit 3 Embedded Assessment 2 In the novel â€Å"Things Fall Apart†, Chinua Achebe teaches us that two cultures are unable to thrive together when they are forcing themselves onto the other through his use of the main protagonist, Okonkwo. This novel, â€Å"Things Fall Apart†, is about the African culture of the Ibo people being invaded by western influences in which Okonkwo is trapped within the feud. This book depicts differences between the two colliding cultures, Okonkwo’s culture, and his response to the newly changing environment to present Achebe’s theme. A repeating pattern shown in â€Å"Things Fall Apart† is that the western cultures greatly differentiate from the Ibo traditions. A†¦show more content†¦Usually, they are ruled by their gods, but the invaders sense that as ridiculous and offers a â€Å"better† way to bring justice with administers. These two contrasting characteristics between the lifestyles sparked the kickof f of Achebe’s theme of cultures forcing themselves onto each other. In the book, the western missionaries were invading the Ibo culture. The main protagonist, Okonkwo, was a famous Ibo man known in the land. He sternly follows all of his tribe’s customs and is famous for being a powerful worker of a high title. Achebe described Okonkwo by saying â€Å"Nwoye and Ikemefuna would listen to Okonkwo’s stories about trial wars, or how, years ago, he had stalked his victim, overpowered him, and obtained his first human head.† (Achebe 54) to show that he is extremely belligerent. This warlike attribute will later play a role in Okonkwo’s response to the dramatic change. A feature shared by both lifestyles was a unique judicial system. In the book, the Ibo justice system was based on judgement from their several gods, rather than under a queen. An example of this divine judgement is when Achebe says â€Å"Okonkwo did as the priest said. He also took with him a